I am surprised that you would have any trouble at all getting Unique to ignite consistantly with any of the standard rifle primers, such as Remington, Winchester, CCI, etc. I would suspect that you have not been consistant in getting the powder fully back in the case, OR, that you are encountering a common problem with these guns, that is, that you have to get muzzle velocities up to a minimum velocity before bullets quit tumbling. For most suitable bullets in my gun that minimum has been 1300-1350 fps. For some bullets I have yet to find a load that does not give tumbling bullets -- granted, these poorly performing bullets are undersized, being 0,321-0,323, that is, 32-40 or 8X57 Mauser caset bullets. I have yet to try any mantled bullets.
I have been using Reloader 22 for at least 20 years in 7X57 and 7X57R. There are lots of data for those "twins" and especially for even larger capacity cartriges. Some of those loads were full case, compressed and never had a problem with ignition. A simple extrapolation from cartridges like 7X57 to 8X58RD, based on difference in case volumes indicates that moderate loads of Reloader 22 will have chamber pressures below 30.000 psi. I go even a bit lower than this in a rather tight chambered 8X58RD with 210 grain cast GC bullets. Velocities are quite low, about 1750 FPS from 33 inch barrels, cases fall out of chamber, groups are as good as I can shoot with the military sights, that is about 3-4 inches at 150 meters.
FYI, burn rate for Reloader 22 is very close to that of Norma MRP.
I think the reason you are not getting more responses is that what most (all?) of us know has already been posted on threads extant on this board.
Niklas