All you stubby-fingered girlie-handed old geezers! I've prolly' got smaller hands than any of you & have no problem with that big ol hog-buster grip on my Glocks. Never fear, if you still hold to that old "Glocks' too big fer me" tome, a new player is out there with some comfier hi cap .45 ACP polymer handles: The Springfield XD. I got an XD-45 Tactical earlier this summer & was initially put off by the crappy trigger. after the sear/springs upgrade, I'm happy with the XD & consider it (for now) approaching equal to the superb accuracy of my Glock 21's.
When you get a chance, go feel an XD-45. Nothing compares with a comfortable handling & accurate .45ACP & from what my little girlie paws have found, the XD fills the bill for the grip-challenged.
For years I regarded the .40 S&W as a big PITA to shoot because of the squirrelly muzzle flip. .357 Sig isn't any better. Last year a shooting buddy bought his first new handgun - Compact Glock in .40 S&W. Gotta be the worst combo - muzzle flippin' .40 cal + a compact size, which ought to magnify all the discomforts ... In theory, yes. In actual trial, when he begged me to shoot it, it was really pleasant and more accurate than I'd ever expect - my first 5 rounds were all in the black on a 50 ft. target. With that being the case, I'd recommend a .40 Glock & would buy one if I needed something less than a .45 & bigger than 9mm. The Glock changed my mind altogether about the .40 S&W.